PurposeTo use the power of knowledge acquisition and machine learning in the development of a collaborative computer classification system based on the features of age-related macular degeneration (AMD).MethodsA vocabulary was acquired from four AMD experts who examined 100 ophthalmoscopic images. The vocabulary was analyzed, hierarchically structured, and incorporated into a collaborative computer classification system called IDOCS. Using this system, three of the experts examined images from a second set of digital images compiled from more than 1000 patients with AMD. Images (...) were annotated, and features were identified and defined. Decision trees, a machine learning method, were trained on the data collected and used to extract patterns. Interrelationships between the data from the different clinicians were investigated.ResultsSix drusen classes in the structured vocabulary were largely sufficient to describe all the identified features. The decision trees classified the data with 76.86% to 88.5% accuracy and distilled patterns in the form of hierarchical trees composed of 5 to 15 nodes. Experts were largely consistent in their characterization of soft, and to a lesser extent, hard drusen, but diverge in definition of other drusen. Size and crystalline morphology were the main determinants of drusen type across all experts.ConclusionsMachine learning is a powerful tool for the characterization of disease phenotypes. The creation of a defined feature set for AMD will facilitate the development of an IDOCS-based classification system. (shrink)

In this working paper, we discuss why researchers and policymakers need to better understand how different theoretical accounts of stability lead to different frameworks of analysis. Though ubiquitously mentioned, stability remains an under-theorized notion in security studies. Expert accounts tend to present stability as a generic description, readily applicable to most political phenomena Ð a stabilized state, a stable region, an unstable society. While seemingly equivocal, such uses exhibit different conceptualizations, exhibiting different features and demanding multiple research programs. To date, (...) most accounts of stability tend to take stability to be an (unconstructed) natural phenomenon or a non-derivative social construction. In this introductory paper, we claim that there is a third way to account for stability that remains unexplored in security studies. Simply put, it involves taking stability to be a derivative social construction (i.e., systemic fallout). We then argue that this alternative account should serve as the theoretical basis for an independent research program within stability studies. (shrink)

In this far-reaching essay, historian Michael Edward Moore examines modernity as an historical epoch following the end of the medieval period -- and as a "messianic concept of time." In the early twentieth century, a debate over the meaning and origins of modernity unfolded among the philosophers Ernst Cassirer, Hans-Georg Gadamer and Hans Blumenberg. These thinkers tried to resolve the puzzle of the fifteenth-century master Nicholas of Cusa. Was Cusanus the last great medieval thinker, his ideas a summa (...) of medieval tradition? Or was he a mysterious epochal figure, seated at one end of the bridge leading to modern thought? Nicholas of Cusa lived during a time of historical and existential crisis, or kairos, when medieval governments and cherished sources of unity were shaken. Likewise, the debate over his significance took place during a later phase of crisis for Europe, in the decades before and after the Second World War, when the collapse of European civilization was witnessed. Moore argues that modernity, so intently examined as an historical and spiritual problem, has significance for our contemporary sense of crisis. (shrink)

Various scholars have argued that the rise of modern information technology over the past century has coincided with a steady decline of traditional methods of learning and interpretation, and has contributed to the general sense of “worldlessness” or anomie. In the words of Paul Ricoeur, “we are overwhelmed by a flood of words, by polemics, by the assault of the virtual, which today create a kind of opaque zone.” Philology, the ancient discipline that grew in the past two centuries to (...) encompass literary study, linguistics, and intellectual history, was originally conceived as a return to the past with the aim of retrieving the knowledge of bygone times. While the recent revival of interest in philology recognizes its importance to the humanities, it remains unnamed as such. The aim of my exploration of the history and practices of philology is to suggest how it can reinstate the presence of the past. With its attentiveness to language—undertaken in the silent spaces of private study, archive, and library—philology not only confirms the presence of the dead but also enacts a more fundamental return to “world.”. (shrink)

Name der Zeitschrift: Millennium Jahrgang: 9 Heft: 1 Seiten: 277-298.

Drawing on a comprehensive, pan-national analysis of the corporatization of Canadian universities, as well as the notions of ‘parrhesiastic’ mentorship and practice, the authors examine the effects of the corporatized university, its implications for graduate nursing education and nursing's relative silence on the subject. With the preponderance of business interests, the increasing dependence of universities on industry funding, cults of efficiency, research intensivity, and the pursuit of profit so prevalent in today's corporatized university, we argue that philosophical presuppositions so crucial (...) to critical teaching, research, and reflection on nursing as a discipline are troublingly losing ground. We lament the erosion and fragmentation of philosophy, politics, and ethics as foundations for graduate education, which are increasingly perceived as less valuable, problematic, and in some cases, even burdensome. The effect of corporatization is the suppression of the critical engagement required of faculty in the everyday workings of institutions. We argue that, when the ideals of intellectual freedom, academic responsibility, duty, and obligation, as supported by philosophical thought, are smothered by the normalizing power of corporatized research agendas, philosophical approaches to inquiry and knowledge development become marginalized as scholars find themselves floundering in the face of a seeming ‘philosophy lost’. (shrink)

Michael A. Petersa and Fazal Rizvib aBeijing Normal University, Beijing, PR China; bMelbourne University, Melbourne, Australia Our minds are still racing back and forth, longing for a return to ‘no...

The contributions in this volume map out how technologies are used and designed to plan, maintain, govern, demolish, and destroy the city. The chapters demonstrate how urban technologies shape, and are shaped, by fundamental concepts and principles such as citizenship, publicness, democracy, and nature. The many authors herein explore how to think of technologically mediated urban space as part of the human condition. The volume will thus contribute to the much-needed discussion on technology-enabled urban futures from the perspective of the (...) philosophy of technology. This perspective also contributes to the discussion and process of making cities ‘smart’ and just. This collection appeals to students, researchers, and professionals within the fields of philosophy of technology, urban planning, and engineering. (shrink)

The rise of managerialism within healthcare systems has been noted globally. This paper uses the findings of a scoping study to investigate the management of poor performance among nurses and midwives in the United Kingdom within this context. The management of poor performance among clinicians in the NHS has been seen as a significant policy problem. There has been a profound shift in the distribution of power between professional and managerial groups in many health systems globally. We examined literature published (...) between 2000 and 10 to explore aspects of poor performance and its management. We used Web of Science, CINAHL, MEDLINE, British Nursing Index, HMIC, Cochrane Library and PubMed. Empirical data are limited but indicate that nurses and midwives are the clinical groups most likely to be suspended and that poor performance is often represented as an individual deficit. A focus on the individual as a source of trouble can serve as a distraction from more complex systematic problems. (shrink)

The majority of food in the US is distributed through global/national supply chains that exclude locally-produced goods. This situation offers opportunities to increase local food production and consumption and is influenced by constraints that limit the scale of these activities. We conducted a study to assess perspectives of producers and consumers engaged in food systems of a major Midwestern city. We examined producers’ willingness to include/increase cultivation of local foods and consumers’ interest in purchasing/increasing local foods. We used focus groups (...) of producers (two groups of conventional farmers, four local food producers) and consumers (three conventional market participants, two locavores) to pose questions about production/consumption of local foods. We transcribed discussions verbatim and examined text to identify themes, using separate affinity diagrams for producers and consumers. We found producers and consumers are influenced by the _status quo_ and real and perceived barriers to local foods. We also learned participants believed increasing production and consumption of local foods would benefit their community and creating better infrastructure could enhance efforts to scale up local food systems. Focus group participants also indicated support from external champions/programs could support expansion of local foods. We learned that diversifying local food production was viewed as a way to support local community, increase access to healthy foods and reduce environmental impacts of conventional production. Our research indicates that encouraging producers and consumers in local food systems will be more successful when support for the local community is emphasized. (shrink)

Practically every contemporary mainstream scientist presumes that all aspects of mind are generated by brain activity. We demonstrate the inadequacy of this picture by assembling evidence for a variety of empirical phenomena which it cannot explain. We further show that an alternative picture developed by F. W. H. Myers and William James successfully accommodates these phenomena, ratifies the common sense view of ourselves as causally effective conscious agents, and is fully compatible with contemporary physics and neuroscience.

(1) For much of this century, moral philosophy has been constrained by the supposed absolute gap between is andought, and the consequent belief that the facts of life cannot of themselves yield an ethical blueprint for future action. For this reason, ethics has sustained an eerie existence largely apart from science. Its most respected interpreters still believe that reasoning about right and wrong can be successful without a knowledge of the brain, the human organ where all the decisions about right (...) and wrong are made. Ethical premises are typically treated in the manner of mathematical propositions: directives supposedly independent of human evolution, with a claim to ideal, eternal truth. (shrink)

This article investigates a high-profile and ongoing dilemma for healthcare professionals, namely whether the existence of a duty of care to genetic relatives of a patient is a help or a hindrance in deciding what to do in cases where a patient’s genetic information may have relevance to the health of the patient’s family members. The English case ABC v St George’s Healthcare NHS Trust and others considered if a duty of confidentiality owed to the patient and a putative duty (...) of care to the patient’s close relatives could coexist in this context. This article examines whether embracing the concept of coexisting duties could enable HCPs to respect duties in line with their clinical judgement, thereby providing legal support and clarity to professionals to allow them to provide the best possible genetics service to both the patient and their family. We argue that these dual duties, framed as a novel, composite duty to consider the interests of genetic relatives, could allow HCPs to exercise and act on their professional judgements about the relative value of information to family members, without fears of liability for negligence or breach of confidence. (shrink)

A formula is a contingent logical truth when it is true in every model M but, for some model M , false at some world of M . We argue that there are such truths, given the logic of actuality. Our argument turns on defending Tarski’s definition of truth and logical truth, extended so as to apply to modal languages with an actuality operator. We argue that this extension is the philosophically proper account of validity. We counter recent arguments to (...) the contrary presented in Hanson’s ‘Actuality, Necessity, and Logical Truth’ (Philos Stud 130:437–459, 2006 ). (shrink)

Technology is no stranger to the city. Cities are planned, built, maintained, governed, demolished, and destroyed by technical means. Yet, the city has yet to receive much attention within the philosophy of technology. This volume addresses this gap, and in doing so contributes to the much-needed discussion on technology-enabled urban futures from the perspective of the philosophy of technology. In this introductory chapter, the larger volume is introduced by reflecting on the rationale and need for such a collection, sketching the (...) main themes analyzed throughout, and providing an overview of the contributions. (shrink)

(1) For much of this century, moral philosophy has been constrained by the supposed absolute gap between is andought, and the consequent belief that the facts of life cannot of themselves yield an ethical blueprint for future action. For this reason, ethics has sustained an eerie existence largely apart from science. Its most respected interpreters still believe that reasoning about right and wrong can be successful without a knowledge of the brain, the human organ where all the decisions about right (...) and wrong are made. Ethical premises are typically treated in the manner of mathematical propositions: directives supposedly independent of human evolution, with a claim to ideal, eternal truth. (shrink)

One objective of this paper is the determination of the proof-theoretic strength of Martin-Löf's type theory with a universe and the type of well-founded trees. It is shown that this type system comprehends the consistency of a rather strong classical subsystem of second order arithmetic, namely the one with Δ 2 1 comprehension and bar induction. As Martin-Löf intended to formulate a system of constructive (intuitionistic) mathematics that has a sound philosophical basis, this yields a constructive consistency proof of a (...) strong classical theory. Also the proof-theoretic strength of other inductive types like Aczel's type of iterative sets is investigated in various contexts.Further, we study metamathematical relations between type theories and other frameworks for formalizing constructive mathematics, e.g. Aczel's set theories and theories of operations and classes as developed by Feferman. (shrink)

Universities have long played an important role in preparing thinkers and leaders who go on to have significant impact around the world. But if the world needs wise thinkers and good leaders, then how might modern universities educate leaders of character, particularly in a pluralistic context where many educators are reluctant to see the university as a site of moral formation? This article shares insights from one specific program, the Oxford Global Leadership Initiative, an extra-curricular program that seeks to help (...) diverse cohorts of graduate students develop the ethical qualities of character needed for leaders to serve the common good. Drawing upon qualitative data collected over three years of program activity to illuminate and illustrate our argument, we address three questions: Can virtues of character necessary for good leadership be cultivated in a university setting among a culturally diverse group of students? How can a character-based leadership program meet the particular developmental needs of “emerging adults”? and How might the program’s impact translate into society and culture? We conclude that a program integrating character and leadership can make valuable contributions to the ethical and professional development of postgraduate students. (shrink)

Utilizing the writings of Pierre Bourdieu and Sheldon Wolin,this paper introduces a special issue on ``Educational Rights andEntitlements.'' Its purpose is to characterize and critique `the box ofliberalism' that both advances and constrains what is conceived andenacted in education. Following it are a set of significantcontributions from the sixth biennial conference of the InternationalNetwork of Philosophers of Education, August 1998, Ankara.

Karen Bennett has recently argued that the views articulated by Linsky and Zalta (Philos Perspect 8:431–458, 1994) and (Philos Stud 84:283–294, 1996) and Plantinga (The nature of necessity, 1974) are not consistent with the thesis of actualism, according to which everything is actual. We present and critique her arguments. We first investigate the conceptual framework she develops to interpret the target theories. As part of this effort, we question her definition of ‘proxy actualism’. We then discuss her main arguments that (...) the theories carry a commitment to actual entities that do not exist. We end by considering and addressing a worry that might have been the driving force behind Bennett’s claim that Linsky and Zalta’s view is not fully actualistic. (shrink)

This paper considers how surprise (or its lack) can be cast as a metacognitive signal with an adaptive function in learning new knowledge and revising belief networks. It reviews the phenomena that may hinder this signal (e.g., hindsight bias) and argues for its extrinsic exploitation in instructional and educational contexts by educators, journalists and parents, who might train learners to internalize the use of surprise to drive explanation‐based learning.

This article describes some potential uses of Bayesian estimation for time-series and panel data models by incorporating information from prior probabilities in addition to observed data. Drawing on econometrics and other literatures we illustrate the use of informative “shrinkage” or “small variance” priors while extending prior work on the general cross-lagged panel model. Using a panel dataset of national income and subjective well-being we describe three key benefits of these priors. First, they shrink parameter estimates toward zero or toward each (...) other for time-varying parameters, which lends additional support for an income → SWB effect that is not supported with maximum likelihood. This is useful because, second, these priors increase model parsimony and the stability of estimates and thus improve out-of-sample predictions and interpretability, which means estimated effect should also be more trustworthy than under ML. Third, these priors allow estimating otherwise under-identified models under ML, allowing higher-order lagged effects and time-varying parameters that are otherwise impossible to estimate using observed data alone. In conclusion we note some of the responsibilities that come with the use of priors which, departing from typical commentaries on their scientific applications, we describe as involving reflection on how best to apply modeling tools to address matters of worldly concern. (shrink)

We agree with Heyes that an explanation of human uniqueness must appeal to cultural evolution, and not just genes. Her account, though, focuses narrowly on internal cognitive mechanisms. This causes her to mischaracterize human behavior and to overlook the role of material culture. A more powerful account would view cognitive gadgets as spanning organisms and their (shared) environments.

This paper is the first in a series whose objective is to study notions of large sets in the context of formal theories of constructivity. The two theories considered are Aczel's constructive set theory and Martin-Löf's intuitionistic theory of types. This paper treats Mahlo's π-numbers which give rise classically to the enumerations of inaccessibles of all transfinite orders. We extend the axioms of CZF and show that the resulting theory, when augmented by the tertium non-datur, is equivalent to ZF plus (...) the assertion that there are inaccessibles of all transfinite orders. Finally, the theorems of that extension of CZF are interpreted in an extension of Martin-Löf's intuitionistic theory of types by a universe. (shrink)

Michael A. PetersBeijing Normal UniversityMy deepest condolences to Pepe, Dom and Marcus and to Jim’s grandchildren. Tina and I spent a lot of time at the Marshall family home, often attending dinn...